Ottawa, ON / Business Wire / February 24, 2020 / – Avivagen Inc.  (TSXV:VIV) (Avivagen”), a life sciences corporation focused on developing and commercializing products for livestock, companion animal and human applications that enhance feed intake and safely support immune function, thereby supporting general health and performance, is pleased to announce positive and statistically significant results from its recently completed New Zealand dairy trial that demonstrated OxC-beta™ Livestock’s contribution against sub-clinical mastitis.

Mastitis is one of the costliest diseases for treatment in the dairy industry, as animals infected with mastitis must be treated by antibiotics, requiring that the infected dairy cows be removed from milk production until fully healthy in order to ensure that their milk does not contain antibiotics.

“We have assessed a number of compounds in terms of their ability to help clear sub clinical mastitis, and this is the first time we have seen a positive effect.”” said Scott McDougall, BSc(Vet), BVSc, PhD; Managing Director of Cognsoco.

“In the United States alone mastitis costs dairy producers more than $2 billion in lost production each year, due in large part to the use of product-contaminating antibiotics for treatment. A non-antibiotic solution that targets the cow’s own immune system as a strategy for preventing and treating of subclinical mastitis has the real-world potential to save billions annually for the global dairy industry1,” says Kym Anthony, Chief Executive Officer of Avivagen. “We are extremely excited that these results show OxC-betaTM Livestock is a viable and safe alternative for dairy producers in high quality markets like New Zealand and others around the world. This is an important new application of OxC-betaTM Livestock that can promote both improved physical health in dairy cows and improved financial health for producers worldwide.”

The trial was conducted over 42 days at four commercial dairy farms on the North Island of New Zealand by Cognosco, a veterinary services and research group working closely with the New Zealand dairy industry. Highlights from this trial, which began in September 2019, include:

Combined with results of an earlier China dairy trial, the New Zealand trial reaffirms the significant benefits that OxC-betaTM Livestock can provide to dairy producers and support the application of OxC-betaTM Livestock in dairy cattle.  Dairy is a large, high value industry and these positive trial results will contribute significantly to Avivagen’s marketing efforts in countries where OxC-betaTM Livestock is already approved, such as the U.S., New Zealand and Mexico, and which are among the world’s largest dairy milk producing nations2. Additionally, it is estimated that mastitis in cows costs Canada’s dairy industry $400 million per year3 and has an even greater impact in other large volume markets.

About Avivagen
Avivagen is a life sciences corporation focused on developing and commercializing products for livestock, companion animal and human applications. By unlocking an overlooked facet of β-carotene activity, a path has been opened to safely and economically support immune function, thereby promoting general health and performance in animals.  Avivagen is a public corporation traded on the TSX Venture Exchange under the symbol VIV and is headquartered in Ottawa, Canada, based in partnership facilities of the National Research Council of Canada and Charlottetown, Prince Edward Island. For more information, visit www.avivagen.com. The contents of the website are expressly not incorporated by reference in this press release.

About OxC-beta™ Technology and OxC-beta™ Livestock
Avivagen’s OxC-beta™ technology is derived from Avivagen discoveries about β-carotene and other carotenoids, compounds that give certain fruits and vegetables their bright colours. Through support of immune function the technology provides a non-antibiotic means of promoting health and growth. OxC-beta™ Livestock is a proprietary product shown to be an effective and economic alternative to the antibiotics commonly added to livestock feeds. The product is currently available for sale in the United States, Philippines, Taiwan, New Zealand, Thailand, Australia and Malaysia.

Avivagen’s OxC-beta™ Livestock product is safe, effective and could fulfill the global mandate to remove all in-feed antibiotics as growth promoters. Numerous international livestock trials with poultry and swine using OxC-beta™ Livestock have proven that the product performs as well as, and, sometimes, in some aspects, better than in-feed antibiotics.

Forward Looking Statements
This news release includes certain forward-looking statements that are based upon the current expectations of management. Forward-looking statements involve risks and uncertainties associated with the business of Avivagen Inc. and the environment in which the business operates. Any statements contained herein that are not statements of historical facts may be deemed to be forward-looking, including those identified by the expressions aim”, anticipate”, appear”, believe”, consider”, could”, estimate”, expect”, if”, intend”, goal”, hope”, likely”, may”, plan”, possibly”, potentially”, pursue”, seem”, should”, whether”, will”, would” and similar expressions. Statements set out in this news release relating to the possibility that New Zealand will use OxC-beta Livestock in dairy production, that these results will lead to expected growth of demand and sales of OxC-beta within New Zealand  or other markets in general, the possibility for deployment or launch of OxC-beta™ Livestock in new jurisdictions around the world or for it to replace antibiotics in livestock feeds as well as fill a critical need for health support in certain livestock applications where antibiotics are precluded, Avivagens intention to accelerate market access and the commercial uptake of its OxC-beta™ Livestock product and the size of market opportunities are all forward-looking statements. These forward-looking statements are subject to a number of risks and uncertainties that could cause actual results or events to differ materially from current expectations. For instance, neither New Zealand nor any other country is under any obligation to purchase product from Avivagen or to increase its purchases and could cease or reduce its purchases at any time, inquiries from potential new customers may not result in orders for Avivagens products and field trials underway may not have anticipated outcomes,  demand for Avivagens products in New Zealand and other markets in general may not continue to grow and could decline, Avivagens products may not gain market acceptance or regulatory approval in new jurisdictions or for new applications and may not be widely accepted as a replacement for antibiotics in livestock feeds, new market access may not occur in the timeline or manner expected by Avivagen and the market opportunities may not be as large as Avivagen anticipates due to many factors, many of which are outside of Avivagens control.  Readers are referred to the risk factors associated with the business of Avivagen set out in Avivagens most recent managements discussion and analysis of financial condition available at www.SEDAR.com. Except as required by law, Avivagen assumes no obligation to update the forward-looking statements, or to update the reasons why actual results could differ from those reflected in the forward-looking statements.

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

For more information:
Avivagen Inc.
Drew Basek
Director of Investor Relations
100 Sussex Drive, Ottawa, Ontario, Canada K1A 0R6
Phone: 416-540-0733
E-mail: d.basek@avivagen.com

Kym Anthony
Chief Executive Officer
100 Sussex Drive, Ottawa, Ontario, Canada K1A 0R6
Head Office Phone: 613-949-8164
Website: www.avivagen.com

Copyright © 2020 Avivagen Inc. OxC-beta™ is a trademark of Avivagen Inc.

1 https://thecattlesite.com/focus/thermo-fisher-scientific/2335/bovine-diagnostics-how-much-does-mastitis-cost-dairy-producers-annually
2 https://www.betterfarming.com/online-news/400-million-year-cost-mastitis-canada%E2%80%99s-dairy-cows-61466
3 https://www.statista.com/statistics/268191/cow-milk-production-worldwide-top-producers/